Angiotensin Receptor Blockers (ARB)

Last updated 03.11.12

 

Index

 

Definition

-  Angiotensin receptor blockers

 

Features

-  May be used interchangeably w Angiotension Converting Enzyme Inhibitor (ACEI)

 

Mechanism

-  Block action of angiotensin on receptors

 

Indications

-  HTN

-  DM nephropathy

-  CCF

-  Left ventricular hypertrophy

 

Drugs

-   

 

Side Effects

-  Hypotension

-  Hyperkalaemia

-  Headache

-  Dizziness

-  Fatigue

-  Nausea

-  Renal impairment

 

Contraindications/Precautions

-  Renal artery stenosis

-  Impaired renal function (ARF, CRF)

-  Pregnancy

 

Dose

-  HTN

-  Candesartan 4-32mg daily

-  Irbesartan 75-300mg daily

-  Olmesartan 10-40mg daily

-  Telmisartan 40-80mg daily