Bence Jones Urinary Proteins

Last updated 20.09.12

 

Index

 

Definition

-  Monoclonal Ig light chain protein (paraprotein) found in urine (or blood)

 

Rationale

-  Usually tested w SPEP

-  Bence Jones protein not detected by urine dipstick

 

Procedure

-  Random urine sample OR

-  24hr rine collection (preferred)

-  Protein Electrophoresis

 

Results

-  Negative: normal

-  Positive

-  Multiple Myelmoa (MM)

-  Waldenstroms Macroglobulinaemia

-  Chronic Lymphoblastic Leukaemia (CLL)

-  Amyloidosis

 

 

 

References