Churg Strauss Syndrome

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Features

-  Medium & small vessel vasuclitis w granulomas

-  Particulary skin & lungs, may also be systemic

 

Dx

-  4+ of (85% sensitive, 99% specific)

-  Asthma

-  Eosinophillia >10%

-  Mono/polyneuropathy

-  CXR: migratory or transient opacities

-  Paranasal sinus abnormalities

-  Biopsy: extravascular eosiniphils

 

Ix

- p-ANCA