Human Lymphocytic Antigen – B27

(HLA-B27)

<Pathology>

<Index>

 

 

 

Association

-  Associated w seronegative spondyloarthropathies

-  7% of healthy general population

-  Occular diseases casuing red eye: uveitis, iritis

-  Reactive arthritis, Resiters disease, IBD, psoriatic arthritis

-  Ankylosing Spondylitis

-  +ve in 90-95% pts 

-  Only 1% +ve pts --> Ankylosing Spondylitis