HP Rapid Urease Test

(HUT, CLO)

Last updated 03.11.12

 

Index

 

Rationale

-  Lab test perfomed on gastrointestinal mucosal biopsy at time of gastroscopy to Dx HP

-  Ix of aetiology of suspectd/Dx PUD

 

Features

-  Requires 24hrs for full Dx effect

-  70% + in 2hrs

-  96% at 6hrs

-  Reaction sped up by heat

-  Sens 90%, spec 95%

-  Comparable to histopatholgy

-  Least expensive test to Dx HP

 

Procedure

-  Biopsy sample added to test kit medium at endoscopy

 

 

Results

-  Orange: –ve

-  Pink: HP +ve

-  False –ves

-  PPI, H2RA, Abx (decrease urease activity)