Haloperidol

<Medications>

<Index>

 

 

 

Features

-  Typical class of antipsychotic (1st generation, neuroleptic)

 

Features

-  More side effects & extrapyramidal effects than atypicals

 

Side Effects

-  Hypotension, tachycardia

-  Long QT syndrome

-  Hyperprolactinaemia

-  Blurred vision, dry mouth

-  Urinary retention

-  Tardive dyskinesia

 

Indications

-  Behavioural emergencies

-  Psychotic disorders

-  Shizophrenia

-  Manic phase of Bipolar disorder

-  Tourette syndrome

-  Alcohol withdrawal

-  Agression

-  Vomiting unresponsive to other therapy

-  Malignancy associated intractable nausea

 

Contraindications

-  CNS depression

-  PD

-  Prolactin dependant tumour

 

Dose

-  Max 100mg Daily

-  PO

-  Moderate S/S 1-5mg PO Daily

-  Severe S/S 5-15mg PO Daily

-  Lowest effective dose for shortest duration

-  0.5mg, 1.5mg or 5mg tablets

-  2mg/ml solution

-  IV/IM

-  2-10mg IM/IV up to 1/2 hrly or hrly

-  5mg/ml solution

 

 

 

References

 

MIMS: Haloperidol, Abbreviated PI, November 2011