Iron Overload

Last updated 15.01.14

 

Definition

-  Elevated serum iron levels

 

Features

-

- 

-

 

Causes

-  Haemochromatosis

- Liver disease

- HFE4 gene defect

- Blood tranfusion iron overload

- Chronic anaemia

 

DDx

-  Chronic inflammation: elevated Ferretin

 

Complications

-     

 

Ix

-  Iron studies

-  Ferretin

- Transferrin Saturation

- FBE: anaemia

- Blood Film: Anaemia

- LFTs

- Liver biopsy if Ferretin >1000mcg/L

 

Mx

-  

 

Algorhythm

 

 

 

References

 

 GESA: Haemochormatosis 2007