Iron Overload

Last updated 15.01.14

Definition

- Elevated serum iron levels

Features

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-

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Causes

- Haemochromatosis

- Liver disease

- HFE4 gene defect

- Blood tranfusion iron overload

- Chronic anaemia

DDx

- Chronic inflammation: elevated Ferretin

Complications

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Ix

- Iron studies

- Ferretin

- Transferrin Saturation

- FBE: anaemia

- Blood Film: Anaemia

- LFTs

- Liver biopsy if Ferretin >1000mcg/L

Mx

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References

GESA: Haemochormatosis 2007