Kernicterus (Biliary Encephalopathy)

Last updated 20.09.12

 

Index

 

Definition

-  Chronic permanent neurological sequelae of hyperbilirubinaemia (neonatal jaundice)

-  Kernicterus describes yellow discoloration of brain

 

Features

-  Apoptosis & necrosis of neurons

 

Assocaited S/S

-  Jaundice

-  Neuro

-  Choreoathetoid CP

-  Senosorineural hearing loss

-  Gaze abnormalities

-  Opithotonic reflex

-  Dental enamel dysplasia

 

Mx

-  Changes are permanent +/- reversible componenent?

-  As per Mx of neonatal jaundice

-  Phototherapy

-  Exchange transfusion

 

 

 

References