Thiamine

(Vitamin B1, Pyrophosphate)

<Medications>

<Index>

 

 

 

Features

-  Water soluble vitamin

-  Deficiency tested by RBC transketolase

-  T/2 9-18/7

-  RDI: 1.2mg/day+/- (adult)

 

Dietary Sources

-  Sunflower seeds

-  Tuna & other fish

-  Beans, lentils, corn & peas

-  Fortified breads, cereals & pasta

-  Lean meats: pork

 

Indications

-  EtOH dependance

-  EtOH withdrawal/intoxication: prevents Wernickes

-  Wernickes

-  Hyperemesis gravidum

-  BeriBeri (wet, dry)

-  Ethylene Glycol poisoning

 

Dose

-  EtOH dependance: 200mg IM/IV Stat then 100mg PO Daily

-  EtOH withdrawal/intoxication

-  Dose & route based on diet intake/tolerance

-  Wernickes 500mg IV TDS 3/7

-  BeriBeri 50mg IM Daily 3-5/7

-  Ethylene Glycol poisoning 100mg IV/IM 6/24 unwil well & acidosis resolved