Varicella Zoster Virus (VZV)

Last updated 26/09/12

 

Index

 

Definition

-  Double stranded herpes virus

 

Features

-  Common viral disease

-  Varicella Zoster Virus (VZV) = Human Herpes Virus type 3 (HHV-3)

-  Double stranded DNA virus

-  Vaccine preventable: live attenuated Varivax

-  Upto 95% of adults have antibodies

 

Presentations

-  Chicken Pox

-  Herpes Zoster (Shingles)

-  Varicella in Pregnancy

-  Post Herpetic Neuralgia

 

Ix

-  Tzanck smear or vesicular fluid

-  Giant cells

-  Epithelial cells w eosinophillic intranuclear inclusions

-  Serology

-  IgG: past exposure

-  IgM: recent exposure

 

Mx

-  Notifiable disease in Australia

-  Vaccinations: 18months, 12yrs, pre-pregnancy (if non-immune)